NYSBC - New York Structural Biology Center

Getting Started


These are the NYSBC-affiliated institutions and institutional representatives:

Institution Representative Email
Albert Einstein College of Medicine Hernando Sosa hsosa@aecom.yu.edu
City University of New York Reza Khayat rkhayat@ccny.cuny.edu
Columbia University Bob Grassucci rg2502@columbia.edu
Memorial Sloan Kettering Cancer Center Chris Lima limac@mskcc.org
Mount Sinai School of Medicine Iban Ubarretxena Iban.Ubarretxena@mssm.edu
New York University David Stokes stokes@nyu.edu
Rockefeller University Seth Darst darst@rockefeller.edu
Wadsworth Center Michael Marko mike.marko.em@gmail.com
Weill Cornell Medical College David Eliezer dae2005@med.cornell.edu



If you are a member of any of these affiliated institutions, these MEMBER INSTITUTION SERVICES are covered by Annual Dues:

  • Advanced instrumentation and expertise for Electron Microscopy

  • Training in instrumentation and techniques, including accredited classes and individual instruction

  • Assigned, dedicated instrument time is part of consortium membership – there are no special fees beyond annual membership dues.

PLEASE NOTE: Annual dues do not cover the laboratory supplies and consumables you will need. See LABORATORY SUPPLIES (below).

If you belong to an NYSBC-affiliated institution:

You have access to both the instrumentation and staff resources of the cryo-EM facility at the NYSBC. If you are interested in embarking on an EM project at the Simons Electron Microscopy Center, please follow these steps:

  • 1. CREATE AN ACCOUNT
    Create a SEMC account for yourself with the following form: SEMC Account Registration for yourself. Note: You must create an account from a member institution IP address. Once created you may then log in from anywhere.

  • 2. REGISTER YOUR PROJECT
    Register your project by using your SEMC credentials using the following form: EM Proposal Submission

  • 3. REVIEW OUR INFORMATION
    Read the resources and capabilities of the Simons Electron Microscopy Center on this site: Considerations before beginning a project and Overview of EM Techniques.

  • 4. SCHEDULE A MEETING
    Arrange a meeting with the SEMC staff (email: EMG@nysbc.org) and notify your institution's Operations Committee Member


  • Laboratory Supplies:

    You will need a variety of supplies and consumables. SEMC users are responsible for covering the cost of expendable supplies that they use. While there are supplies in the lab and we will do our best to be cooperative so that your project can continue to move forward, you SHOULD NOT ASSUME THAT THE SUPPLIES YOU NEED WILL BE AVAILABLE IF YOU RUN OUT OR DIDN'T BRING THEM WITH YOU. Sometimes the lab might not have what you need on that day.

    There are two ways to obtain these supplies:
    • Follow the links to the supplies and order them yourself, using your own credit card.

    • Purchase supplies in the form of kits directly from the SEMC lab.

    Payment can be made in one of two ways:
      - Write a check payable to New York Structural Biology Center, Inc., give it to Ashleigh Raczkowski or Kelsey Jordan. Ashleigh and Kelsey can be found in the SEMC lab M-F, 9:00am - 4:00pm. PURCHASE YOUR SUPPLIES PRIOR TO YOUR LAB SESSION.

      - Purchase your kit with a credit card using PayPal. GO TO WWW.PAYPAL.COM and click on "Send Money". Follow the instructions and use your credit card to send money to: Paypalkits@nysbc.org. Please print your receipt and bring it with you to the lab as proof you have paid. PLEASE INCLUDE IN YOUR PAYPAL E-MAIL THE SPECIFIC KIT YOU ARE PURCHASING (i.e., "User Kit", "Krios Cartridge Kit" or "Krios Cartridge Mini-Kit"). Give your printed receipt to the lab and give a copy to Kelsey Jordan or Ashleigh Raczkowski. Kelsey and Ashleigh are available in the SEMC lab M-F, 9:00am - 4:00pm. PURCHASE YOUR SUPPLIES PRIOR TO YOUR LAB SESSION. BE SURE TO BRING YOUR RECEIPT WITH YOU TO YOUR SESSION.
    There are three types of kits:

    STANDARD USER KIT ($205.00)

    The Standard User Kit contains the minimal supplies necessary for a project. To see a list of the Standard User Kit supplies, click here:

    SHOW STANDARD USER KIT SUPPLIES




    NOTE: The Standard User Kit contains the minimal supplies necessary for a project. Your project may have more specific requirements, and you may need to order additional supplies.

    To see a list of the supplies not included in the Standard User Kit, click here:

    SHOW ITEMS NOT IN THE STANDARD USER KIT


    KRIOS CARTRIDGE KIT ($85.00)

    The Krios Cartridge Kit contains the supplies sufficient for 1 clipping from SEMC. SEMC staff have assigned grid clipping days and supplies must be presented or paid for at that time for grids to be clipped and scheduled for upcoming Krios time. We DO accept pre-clipped grids in new AutoGrids, and also grids in new AutoGrids that have been previously imaged using a different Krios. However, we reserve the right to inspect these grids and reject them for loading based on their integrity. Used AutoGrids are NOT permitted because they invalidate our warranty and have the potential to result in many weeks of downtime for the instrument.

    To see a list of the Krios Cartridge Kit supplies, click here:

    SHOW KRIOS CARTRIDGE KIT SUPPLIES


    KRIOS CARTRIDGE MINI-KIT ($69.00)

    The Krios Cartridge Mini-Kit contains all the supplies sufficient for 1 clipping from SEMC EXCEPT the AutoGrid Box. SEMC staff have assigned grid clipping days and supplies must be presented or paid for at that time for grids to be clipped and scheduled for upcoming Krios time. We DO accept pre-clipped grids in new AutoGrids, and also grids in new AutoGrids that have been previously imaged using a different Krios. However, we reserve the right to inspect these grids and reject them for loading based on their integrity. Used AutoGrids are NOT permitted because they invalidate our warranty and have the potential to result in many weeks of downtime for the instrument.

    To see a list of the Krios Cartridge Mini-Kit supplies, click here:

    SHOW KRIOS CARTRIDGE MINI-KIT SUPPLIES




    Member Institutions


    Albert Einstein College Of Medicine
    New York University Logo

    Mount Sinai School Of Medicine

    Columbia University
    Memorial Sloan Kettering Cancer Center
    The Rockefeller University

    Wadsworth Center Logo

    CUNY logo
    Cornell University Logo