Dr. Andy Stewart, University of Limerick
University of Limerick
Electron diffraction tomography (EDT) has been a revelation for the structure solution of nano sized crystals across a vast expanse of materials, including most recently protein crystals, since its introduction in 2009. An overview of the different EDT techniques with some analysis of the strengths and weaknesses of each method, including an exploration of how EDT can be developed further, to improve data quality, the speed of data collection, and most importantly data analysis and structure solution. With a brief look at where EDT sits in the tool box of structural biology with regards to other emerging techniques.