News and Events
News
New Instruments For NCCAT
In September, NYSBC placed orders for three new Krios G3i-Cryo transmission electron microscopes. These microscopes will be part of the new National Center for CryoEM Access and Training, which was funded by [...]
New Construction Underway
We have started construction of a new 5000SQF space that will be the new home of National Center for CryoEM Access and Training which was funded by the NIH Common Fund Transformative High Resolution [...]
The Nobel Prize in Chemistry 2017
The Nobel Prize in Chemistry 2017 was awarded to Jacques Dubochet, Joachim Frank and Richard Henderson "for developing cryo-electron microscopy for the high-resolution structure determination of biomolecules in solution". http://www.nobelprize.org/nobel_prizes/chemistry/laureates/2017/press.html https://www.nobelprize.org/nobel_prizes/chemistry/laureates/2017/press.pdf [...]
New Krios Microscopes
The Krios#1 microscope has been operational despite the construction, and has been producing high quality data more or less continuously. The Krios#2 microscope is now in open beta. The Krios#3 is built, and is currently in a testing [...]
Past Events
Holey Gold Grid Making Workshop
The next Gold Grid Making workshop will be held: December 3, 20192:45pm-5pm SEMC will hold a practical workshop, which provides an overview of making holey gold foils from holey carbon foils supported on gold [...]
The Winter-Spring 2021 EM Course
About the course Electron microscopy in combination with image analysis is increasingly powerful in producing 3D structures of individual molecules and large macromolecular complexes that are unapproachable by other methods. This course [...]
VitroJet: Bridging the Gap in Sample Prep
Giulia Weissenberger, MScApplication Engineer, CryoSol World12:00 PM Tuesday, October 15 Through many exciting developments, cryo-electron microscopy (EM) has become a powerful method to elucidate 3D structures of macromolecular complexes. This knowledge provides valuable insight [...]
Electron Cryotomography Provides Evidence of a Novel Pathway for Tubulin’s Polymerization into Microtubules
Richard McIntosh, Ph.D.Distinguished Professor EmeritusUniversity of Colorado Boulder, Department of Physics12:00 PM - Friday, October 4, 2019 The McIntosh lab has used electron tomography to examine the tips of microtubules (MTs) growing [...]
Local Resolution and Directional Local Resolution: Their many new applications in CryoEM
Jose Maria Carazo, Ph.D. Biocomputing Unit, Head, CNB-CSICSpanish National Center for Biotechnology12:00 PM – Tuesday, August 13, 2019 This forum will be a presentation of the work from the Carazo group on local resolution [...]
The Winter-Spring 2020 EM Course
Please sign up here so we have an accurate headcount of students to book classrooms: https://www.surveymonkey.com/r/WinterCourse20 . About the course Electron microscopy in combination with image analysis is increasingly powerful in producing [...]
Capturing the Sequential Steps of Dynamin-mediated Fission by Cryo-EM: The Mixed Blessing of Helical Polymers
Jenny E. Hinshaw, Ph.D. Senior Investigator, Structural Cell Biology Section, Laboratory of Cell and Molecular Biology, NIDDK 12:00 PM - Thursday, July 11, 2019 Dynamin superfamily proteins (DSPs) are present in all organisms and [...]
SEMC cryoEM course
About the course Electron microscopy in combination with image analysis is increasingly powerful in producing 3D structures of individual molecules and large macromolecular complexes that are unapproachable by other methods. This course [...]
Protein Tyrosine Phosphatases (PTPs) act as important regulators in signaling pathways in all organisms by regulating phosphorylation levels
Jihye JoYale UniversityDepartment of Chemistry 12:00 PM Tuesday, June 25 Main Seminar Room, New York Structural Biology Center Protein Tyrosine Phosphatases (PTPs) are important regulators in signaling pathways in all organisms by regulating [...]
Unique Capabilities of the DE-64 for Cryo-EM
Benjamin Bammes, Ph.D.Direct Electron LP, San Diego, CAJune 24, 201912pm - NYSBC Main Conference Room Over the past five years, electron cryo-microscopy (cryo-EM) has become the most popular and effective technique in [...]