News and Events
News
New Instruments For NCCAT
In September, NYSBC placed orders for three new Krios G3i-Cryo transmission electron microscopes. These microscopes will be part of the new National Center for CryoEM Access and Training, which was funded by [...]
New Construction Underway
We have started construction of a new 5000SQF space that will be the new home of National Center for CryoEM Access and Training which was funded by the NIH Common Fund Transformative High Resolution [...]
The Nobel Prize in Chemistry 2017
The Nobel Prize in Chemistry 2017 was awarded to Jacques Dubochet, Joachim Frank and Richard Henderson "for developing cryo-electron microscopy for the high-resolution structure determination of biomolecules in solution". http://www.nobelprize.org/nobel_prizes/chemistry/laureates/2017/press.html https://www.nobelprize.org/nobel_prizes/chemistry/laureates/2017/press.pdf [...]
New Krios Microscopes
The Krios#1 microscope has been operational despite the construction, and has been producing high quality data more or less continuously. The Krios#2 microscope is now in open beta. The Krios#3 is built, and is currently in a testing [...]
Past Events
Appion Part 1 – Basics and 2D Single Particle Analysis
The Appion Part 1 Workshop provides hands-on training for the Appion single-particle data processing workflow. Appion is a “pipeline” for processing and analysis of EM images; it is integrated with Leginon data [...]
Combination of cryo-EM and genetics to study eukaryotic cilia
Masahide Kikkawa, Department of Cell Biology and Anatomy, Graduate School of Medicine, The University of Tokyo12PM - December 10, 2019 Eukaryotic cilia are complex cell organelles and play important roles in various cell, [...]
Holey Gold Grid Making Workshop
The last Gold Grid Making workshop was held: December 3, 20192:45pm-5pm SEMC will hold a practical workshop, which provides an overview of making holey gold foils from holey carbon foils supported on gold mesh [...]
The Winter-Spring 2021 EM Course
About the course Electron microscopy in combination with image analysis is increasingly powerful in producing 3D structures of individual molecules and large macromolecular complexes that are unapproachable by other methods. This course [...]
VitroJet: Bridging the Gap in Sample Prep
Giulia Weissenberger, MScApplication Engineer, CryoSol World12:00 PM Tuesday, October 15 Through many exciting developments, cryo-electron microscopy (EM) has become a powerful method to elucidate 3D structures of macromolecular complexes. This knowledge provides valuable insight [...]
Electron Cryotomography Provides Evidence of a Novel Pathway for Tubulin’s Polymerization into Microtubules
Richard McIntosh, Ph.D.Distinguished Professor EmeritusUniversity of Colorado Boulder, Department of Physics12:00 PM - Friday, October 4, 2019 The McIntosh lab has used electron tomography to examine the tips of microtubules (MTs) growing [...]
Local Resolution and Directional Local Resolution: Their many new applications in CryoEM
Jose Maria Carazo, Ph.D. Biocomputing Unit, Head, CNB-CSICSpanish National Center for Biotechnology12:00 PM – Tuesday, August 13, 2019 This forum will be a presentation of the work from the Carazo group on local resolution [...]
The Winter-Spring 2020 EM Course
General registration for the 2020 winter course is closed. If you registered for this course through your institution's registrar (with a cutoff in January), then please let us know as we have [...]
Capturing the Sequential Steps of Dynamin-mediated Fission by Cryo-EM: The Mixed Blessing of Helical Polymers
Jenny E. Hinshaw, Ph.D. Senior Investigator, Structural Cell Biology Section, Laboratory of Cell and Molecular Biology, NIDDK 12:00 PM - Thursday, July 11, 2019 Dynamin superfamily proteins (DSPs) are present in all organisms and [...]
SEMC cryoEM course
About the course Electron microscopy in combination with image analysis is increasingly powerful in producing 3D structures of individual molecules and large macromolecular complexes that are unapproachable by other methods. This course [...]