NYSBC - New York Structural Biology Center

Simons Electron Microscopy Center

The Simons Electron Microscopy Center provides expertise and resources for understanding both molecular and cellular structures. Molecular structure determination is enabled by high-end transmission electron microscopes (TEMs), direct detection cameras, and computational support for single particle analysis. Cellular structure determination is enabled by tomographic reconstructions using the TEMs and a focused ion beam (FIB) scanning electron microscope (SEM). SEMC is supported by dues from member institutions as well as the Simons Foundation.


SEMC Renovations Renovations

Krios#2 Room-Table Installed


Krios #3 Room

Major renovations to the SEMC suite will continue through most of July. Our current plan for the renovations is as below, but please bear with us as major changes like these cannot always be held to a strict timeline.

We are preparing for the arrival of Krios#2 and improving the environmental stability for our EM suites. Along with this renovation we have moved the JEOL 1230 to join the FEI TF20 in the Park building of NYSBC. We are also digging pits in the other two microscope rooms to support vibration tables for future microscopes.

The TF20/1230 area will also have an HVAC upgrade in the next few months. Please see our renovations page for more details.

Because of the construction, access to the microscopes will be limited. During this time please email EMG@NYSBC.org to schedule microscope use.

Please bear with us during the next period. We expect that the heavy inside construction work will be completed by the end of June and we will be able to use our control rooms again.

Click here to view an updated renovation schedule.
Click here to to learn about scheduling microscope time during the renovation period.


Appion Part 2 Workshop

A one-day Appion Workshop will be held on July 26, 2016 from 10:00AM to 4:00PM. This Appion Part 2 Workshop is a follow-on to the Part 1 workshop and will focus on 3D initial models and refinement. If you are interested in attending an Appion Part 2 Workshop, please register at: https://www.surveymonkey.com/r/5NK7NGQ. The workshop is limited to 10 attendees.

Holey Gold Grid Workshop

The next Holey-Gold Grid Workshop will be held on August 25th, 2016, from 1:00-3:00PM. Our Holey-gold grid workshop shows users how to make their own holey-gold grids from standard holey carbon gold grids. To register for this workshop, click here: https://www.surveymonkey.com/r/YZQPWH3.

SEMC Forums

Myriam Badr, Ph.D., Application Scientist, Nanotemper Technologies, Cambridge, MA
Exploring protein thermal and colloidal stability by NanoDSF
Thursday, July 21st, 12:00pm
Click here for details.

Dr. Andy Stewart, University of Limerick
Electron diffraction tomography, its many flavors, and applications to beam sensitive specimens.
Monday, August 8th, 12:00pm
Click here for details.

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