NYSBC - New York Structural Biology Center

Simons Electron Microscopy Center

The Simons Electron Microscopy Center provides expertise and resources for understanding both molecular and cellular structures. Molecular structure determination is enabled by high-end transmission electron microscopes (TEMs), direct detection cameras, and computational support for single particle analysis. Cellular structure determination is enabled by tomographic reconstructions using the TEMs and a focused ion beam (FIB) scanning electron microscope (SEM). SEMC is supported by dues from member institutions as well as the Simons Foundation.


SEMC Renovations Cntrl718

Additional wiring being added to the control room


Anti-vibration table being added to Krios#3 room

Major renovations to the SEMC suite will continue through most of July. Our current plan for the renovations is as below, but please bear with us as major changes like these cannot always be held to a strict timeline.

We are preparing for the arrival of Krios#2 and improving the environmental stability for our EM suites. Along with this renovation we have moved the JEOL 1230 to join the FEI TF20 in the Park building of NYSBC. We are also digging pits in the other two microscope rooms to support vibration tables for future microscopes.

The TF20/1230 area will also have an HVAC upgrade in the next few months. Please see our renovations page for more details.

Because of the construction, access to the microscopes will be limited. During this time please email EMG@NYSBC.org to schedule microscope use.

Please bear with us during the next period. We expect that the heavy inside construction work will be completed by the end of June and we will be able to use our control rooms again.

Click here to view an updated renovation schedule.
Click here to to learn about scheduling microscope time during the renovation period.


Laboratory Supplies
There is new information on our "To Start" page regarding how to obtain the consumable laboratory supplies that users are required provide for their projects. To learn more about it, click here.

Tuesday 8/2
New User Training

NewUser This month's New User Training was attended by Bryant Avila, Pu Gao, Madhuri Kalathur, Alice Verchere, and led by Edward Eng. New users are required to attend a group new user training session before use of the facility. We offer these 1-day training sessions the beginning of each month from 9am to 4:30pm. Please email EMG@NYSBC.org to inquire about future training session dates.

Tuesday 7/26
Appion Part 2 Workshop

Appion2 A one-day Appion Workshop was held on July 26, 2016 from 10:00AM to 4:00PM. This Appion Part 2 Workshop was a follow-on to the Part 1 workshop and focused on 3D initial models and refinement. If you are interested in attending an Appion Part 2 Workshop, please register at: https://www.surveymonkey.com/r/5NK7NGQ. The workshop is limited to 10 attendees.

Holey Gold Grid Workshop

The next Holey-Gold Grid Workshop will be held on August 25th, 2016, from 1:00-3:00PM. Our Holey-gold grid workshop shows users how to make their own holey-gold grids from standard holey carbon gold grids. To register for this workshop, click here: https://www.surveymonkey.com/r/YZQPWH3.

SEMC Forums

Prof. Jose-Maria Carazo, Spanish National Center for Biotechnology, Madrid, Spain
Cryo-EM data processing and information integration over the Web
Wednesday, August 24th, 12:00pm
Click here for details.

Dr. Joel Mancuso and Dr. Mark Riccio, Carl Zeiss Microscopy, LLC
Non-invasive High Resolution 3D X-ray Microscopy for Life Sciences, Materials Science, and Engineering.
Thursday, August 18th, 12:00pm
Click here for details.

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